The Big Bang Theory's main character, Sheldon Cooper, is a brilliant but socially inept physicist who frequently makes inappropriate or sexist comments towards his female colleagues and friends. However, actor Jim Parsons explains that Sheldon doesn't know when he's being mean because the part of his brain that should know is getting a wedgie from the rest of his brain.
Over time, Sheldon learns to understand social cues and become more empathetic towards his friends' needs, making him a well-rounded person. Despite his initial dysfunction, Sheldon's relationships with his friends, particularly Leonard and Penny, are what make the show accessible and provide a basis for dynamic between the group.
